Fluorescence pattern recognition for ultrasensitive molecule identification: comparison of experimental data and theoretical approximations

Autor:	K. H. Drexhage, A. Fischer, Jutta Arden-Jacob, R. Müller, Jürgen Wolfrum, Stefan Seeger, M. Köllner
Rok vydání:	1996
Předmět:	Photon Chemistry business.industry General Physics and Astronomy Experimental data Information theory Fluorescence Identification (information) Optics Pattern recognition (psychology) Molecule Physical and Theoretical Chemistry Absorption (electromagnetic radiation) Biological system business
Zdroj:	Chemical Physics Letters. 250:355-360
ISSN:	0009-2614
DOI:	10.1016/0009-2614(96)00031-0
Popis:	A concept taken from information theory is applied to ultrasensitive fluorescence detection and identification of molecules. The theoretical misidentification probability is compared to the experimental error probability. It is found that 350 photons are sufficient to distinguish dye molecules with nearly identical absorption and emission properties but with different fluorescence lifetimes with an accuracy of 1 misidentification in 10 4 experiments. Thus we demonstrate the experimental usefulness of the Kullback-Leibler minimum discrimination information for the identification of molecules.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a13470a2a1f0a8b89a00aad07be8b825 https://doi.org/10.1016/0009-2614(96)00031-0 Zobrazit plný text záznamu Full Text from ScienceDirect