Study of Phosphate Excretion by the Stop-Flow Technique

Autor:	J.P. De Koster, M. De Myttenaere, Lambert Pp, R.J. Kahn, Vanderveiken F
Rok vydání:	1964
Předmět:	medicine.medical_specialty Reabsorption business.industry Phosphorus Renal function chemistry.chemical_element Parathyroid hormone Phosphate Excretion chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine Stop flow technique business Hormone
Zdroj:	Nephron. 1:103-117
ISSN:	2235-3186 1660-8151
DOI:	10.1159/000179323
Popis:	The stop-flow technique has been applied to the dog in an attempt to rule out tubular secretion of phosphate and to locate the site of action of parathyroid hormone (P.T.H.) on the renal tubule. Under the experimental conditions used, no significant inward transtubular movement of P32 could be demonstrated, ruling out tubular secretion of phosphate. Stop-flow experiments performed in parathyroidectomized dogs before and after P.T.H. administration demonstrated inhibition of phosphorus reabsorption by the hormone. In addition, the stop-flow pattern indicated that this phenomenon took place mainly in the distal part of the proximal tubules.
Databáze:	OpenAIRE
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