Effect of peanut oil and nandrolone on serum cytokines in pubertal term rats

Autor:	Seyfullah Haliloglu, Erdal Tasgin
Rok vydání:	2017
Předmět:	medicine.medical_specialty food.ingredient General Veterinary business.industry medicine.medical_treatment Nandrolone decanoate Serum cytokine Cytokine Endocrinology food Nandrolone Internal medicine Male rats medicine Peanut oil Animal Science and Zoology Cytokine synthesis business medicine.drug
Zdroj:	Indian Journal of Animal Research.
ISSN:	0976-0555 0367-6722
DOI:	10.18805/ijar.v0iof.7819
Popis:	The purpose of this study was to determine the effect of nandrolone on cytokine levels in pubertal term female and male rats. Totally 60 pubertal term Spraque Dawley rat (30/30 female/male) were divided into 3 equal groups. Control group received no treatment. PO group received intraperitoneally peanut oil every 5 days with an intervening gap of 2 days where no treatment was given. ND group received intraperitoneally nandrolone decanoate (10 mg/kg) within peanut oil like PO group. At the end of the four weeks, blood samples were obtained. Serum cytokine levels were measured by ELISA. Peanut oil significantly (P less than 0.05) increased serum levels of interleukin-1â and interleukin-6 in pubertal term male rats, while nandrolone decanoate had no any effect on the cytokine levels compared to experimental groups. It may be stated that nandrolone decanoate has no excessive inducer effect on the cytokine synthesis in pubertal male and female term.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a114547afc5f0b1a9cadd2da1b8d29b0 https://doi.org/10.18805/ijar.v0iof.7819 Zobrazit plný text záznamu