Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla

Autor:	Ho Kyung Kim, Sang Hyun Sung, Sang Du Kim, Eun Sun Yang, Ki Yong Lee, Seung Hyun Kim, Young Choong Kim
Rok vydání:	2010
Předmět:	Chromatography Central composite design Chemistry Extraction (chemistry) Analytical chemistry Filtration and Separation Charged aerosol detector Method development High-performance liquid chromatography Liriope platyphylla Analytical Chemistry Aerosol
Zdroj:	Separation and Purification Technology. 71:168-172
ISSN:	1383-5866
DOI:	10.1016/j.seppur.2009.11.016
Popis:	Method development based on pressurized liquid extraction technique was investigated for the extraction of spicatoside A from Liriope platyphylla. Determination of spicatoside A was carried out by high performance liquid chromatography coupled with charged aerosol detector. Central composite design consisting of 15 experimental points in triplicate was applied to evaluated the effects of three independent variables, namely extraction time (min), extraction temperature (°C) and ethanol concentration (%) on the acquired content of spicatoside A. Response surface analysis indicated that the highest predicted content of spicatoside A might be 0.0161% of the optimized extract at extraction time 20 min, extraction temperature 130 °C and ethanol concentration 86%. Under this optimal condition, the experimental value was 0.0157%, which agrees with the predicted one by analysis of variance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a106ffeabfccfe7f11cc7d10161e77ea https://doi.org/10.1016/j.seppur.2009.11.016 Zobrazit plný text záznamu Full Text from ScienceDirect