Retention in supercritical fluid chromatography on cyano-bonded silica columns
| Autor: | Roger M. Smith, David A. Briggs, Simon Cocks, Vince G. Evans, Mohd Marsin Sanagi |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
chemistry.chemical_classification
Chromatography Aryl Hydrophilic interaction chromatography Biochemistry Capacity factor Analytical Chemistry chemistry.chemical_compound Silanol Homologous series chemistry Electrochemistry Supercritical fluid chromatography Environmental Chemistry Methanol Spectroscopy Alkyl |
| Zdroj: | The Analyst. 116:1281 |
| ISSN: | 1364-5528 0003-2654 |
| DOI: | 10.1039/an9911601281 |
| Popis: | The factors affecting the retention of analytes in supercritical fluid chromatography on cyano-bonded silica columns have been examined by using a homologous series of alkyl aryl ketones and selected aromatic test compounds. Carbon dioxide or methanol-modified carbon dioxide was used as the mobile phase. The retentions of the homologous ketones were consistent with a combination of the normal-phase interactions of the analytes with the polar stationary phase and their volatility. For the test compounds the primary influence appeared to be polar interactions with the free silanol groups on the stationary phase, which were greatly reduced by the addition of methanol to the mobile phase. There were significant differences in the retention properties of four different brands of cyano-bonded stationary phase, which could be related to the extent of coverage of the silica surface. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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