The Role of TNF-α as a Proinflammatory Cytokine in Pathological Processes

Autor:	Alexandrino Pereira dos Santos Neto, Carolina dos Santos Guimarães, Sandra Maria Alves Sayão Maia, Alessandra De Albuquerque Tavares Carvalho, Jair Carneiro Leão, Iliana Lins Quidute, Severino Alves Júnior, Luciano Barreto Silva
Rok vydání:	2019
Předmět:	0301 basic medicine business.industry Inflammation Proinflammatory cytokine 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Immunology Medicine Tumor necrosis factor alpha medicine.symptom business General Dentistry Pathological 030215 immunology
Zdroj:	The Open Dentistry Journal. 13:332-338
ISSN:	1874-2106
DOI:	10.2174/1874210601913010332
Popis:	TNF-α is a member of the vast cytokine family being considered a proinflammatory substance produced many by macrophages and other cells belonging to the innate immunity, many of them classified as indeed Antigen Presenting Cells (APCs) involved in the complex chemotactic process of activation of the adaptive immunity. The aim of this work was to accomplish a literature review concerning the main pathologies that have TNF-α as a modulating agent in other to bring light to the main interactions present in the inflammation installed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a0e1eff16238934cee424a2e5bea04ae https://doi.org/10.2174/1874210601913010332 Zobrazit plný text záznamu