Sildenafil is Safe and Effective for the Treatment of Lower Ureteric Stone with no Major Side Effect

Autor:	Sudeep Raj Kc, Gaurav Devkota, Nirmal Lamichanne, Bhusan Raj Timilsina, Rajiv Shah, Hari Prasad Upadhyay
Rok vydání:	2019
Předmět:	medicine.medical_specialty Ureteric Stone Side effect business.industry Sildenafil Urinary system Incidence (epidemiology) Urology General Medicine Placebo Group B chemistry.chemical_compound Ureter medicine.anatomical_structure chemistry Medicine business
Zdroj:	Birat Journal of Health Sciences. 3:560-564
ISSN:	2542-2804 2542-2758
DOI:	10.3126/bjhs.v3i3.22190
Popis:	INTRODUCTION: Urolithiasis is one of the most common diseases of the urinary tract. Prevalence of urinary stones in a life time is approximately 1% to 15%.Peak age of incidence is 30 years. Male are more commonly affected than female about 2 to 3 times. At the time of presentation 20 % of the calculi are found in the ureter, among which 70% are located in the distal third of the ureter. OBJECTIVE: To study the effect of sildenafil citrate on passage of stone from distal ureter. METHODOLOGY: This is the Quasi experimental study performed in College Of Medical Sciences, Chitwan, Nepal, from February 2017 to February 2018 for a period of one year. First 100 patients of urolithiasis were selected and divided into two groups with the help of lotiery method Group A and Group B. In group A we had patient on placebo and in group B we had patient receiving sildenafil 50 mg once daily and for the period of two weeks. RESULTS: The mean ± standard deviation of stone size was 7.01±1.70mm for treatment group and 6.85±1.56mm for placebo group (p> 0.64) .The stone expulsion rate was 74.5% for treatment group and 41.7% for placebo group (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a0df40b449decc4a801a0b4b7ad2c46b https://doi.org/10.3126/bjhs.v3i3.22190 Zobrazit plný text záznamu