Outcome of Septic Shock in Older Adults After Implementation of the Sepsis “Bundle”

Autor: Ali A. El Solh, Morohunfolu E. Akinnusi, Lilibeth A. Pineda, Leith N. Alsawalha
Rok vydání: 2008
Předmět:
Zdroj: Journal of the American Geriatrics Society. 56:272-278
ISSN: 1532-5415
0002-8614
DOI: 10.1111/j.1532-5415.2007.01529.x
Popis: OBJECTIVES: To evaluate the effect on 28-day mortality of implementation of a sepsis “bundle” protocol for the treatment of older adults with septic shock. DESIGN: Observational prospective study with a historical control group. SETTING: Tertiary care center. PARTICIPANTS: Eighty-seven consecutive patients recruited between May 2004 and February 2007 matched to a historic group identified between March 2001 and April 2004. INTERVENTIONS: Implementation of a sepsis protocol for the management of septic shock. RESULTS: Subjects who were treated according to the sepsis “bundle” had an absolute risk reduction in 28-day mortality of 16% (95% confidence interval (CI)=−31% to −2%). The treatment group received a larger volume of fluid in the first 6 hours of presentation (3,960 ± 1,990 vs 2,490 ± 1,020 mL; P
Databáze: OpenAIRE