A descriptive study on individually titrated levothyroxine in the management of South African hypothyroid patients (DeuTSH)

Autor:	Elsabe J E de Kock, Helena Oosthuizen, Phillip Smuts, Jaco C J Jurgens, Rudy Onia, Hermanus S Schoeman
Rok vydání:	2014
Předmět:	endocrine system medicine.medical_specialty Pediatrics endocrine system diseases business.industry Levothyroxine Predictive value medicine Euthyroid Observational study Intensive care medicine business hormones hormone substitutes and hormone antagonists medicine.drug
Zdroj:	Endocrine Abstracts.
ISSN:	1479-6848
DOI:	10.1530/endoabs.35.p1034
Popis:	This observational study measured the efficacy of individually titrated doses of levothyroxine to achieve a euthyroid state. Target TSH utilised was set at 0.4 – 4.0 mIU/L. (initially 0.4-2.5 mIU/L in younger patients, but adapted after the publication of new hypothyroidism guidelinesiii .) Secondary objectives were the evaluation of mean dose per kg bodyweight to reach euthyroidism, predictive value of initial TSH in determining therapeutic dosage, and assessment of the value of a 25 microgram formulation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a0c01f00580f0cf34c642f151740a1c5 https://doi.org/10.1530/endoabs.35.p1034 Zobrazit plný text záznamu