gem-Dimethylcyclopropanation Using Triisopropylsulfoxonium ­Tetrafluoroborate: Scope and Limitations

Autor:	Michael G. Edwards, Richard J. Paxton, David S. Pugh, Richard J. K. Taylor, Adrian C. Whitwood
Rok vydání:	2008
Předmět:	Chalcone chemistry.chemical_compound Tetrafluoroborate Nitrile Nucleophile Chemistry Reagent Organic Chemistry Nitro Medicinal chemistry Catalysis Isopropyl Sulfone
Zdroj:	Synthesis. 2008:3279-3288
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0028-1083165
Popis:	A new nucleophilic isopropyl transfer reagent, triisopro- pylsulfoxonium tetrafluoroborate, has been prepared and evaluated. Thus, using this reagent and NaH in DMF, a range of electron defi- cient alkenes, including several chalcone analogues, a,b-unsaturat- ed ketones, dienones and quinones, plus a,b-unsaturated esters, nitrile, sulfone and nitro examples, have been converted into the corresponding gem-dimethylcyclopropane compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a09f5f2d90a50f855e90d3d1fe491221 https://doi.org/10.1055/s-0028-1083165 Zobrazit plný text záznamu