Supercritical fluid extraction—Supercritical fluid chroomatography for analysts of a prostglandin: HPMC dispersion

Autor:	Daryl A. Roston
Rok vydání:	1992
Předmět:	Pharmacology animal structures Chromatography Chemistry Organic Chemistry Extraction (chemistry) Supercritical fluid extraction Pharmaceutical Science Drug formulations Dosage form Supercritical fluid Drug Discovery Supercritical fluid chromatography Sample preparation Dispersion (chemistry)
Zdroj:	Drug Development and Industrial Pharmacy. 18:245-255
ISSN:	1520-5762 0363-9045
DOI:	10.3109/03639049209043697
Popis:	An on-line SFE-SFC system was used to extract and chromatograph a synthetic prostaglandin from hydroxypropyl methylcellulose (HPMC), which is a widely used material in controlled-release drug formulations. The only sample preparation for the on-line SFE-SFC analysis of the dispersion was weighing the sample into the extraction vessel insert. The extraction efficiency for a four-minute extraction was approximately 65%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a093b9ae7d85dd14bd932d6f7cc3152d https://doi.org/10.3109/03639049209043697 Zobrazit plný text záznamu