Preliminary single-dose clinical pharmacokinetics of an anti–PD-L1 Probody therapeutic (Pb-Tx) in cancer patients
Autor: | Mark Stroh, Vanessa Huels, Rachel Humphrey, Matthias Will, Beiyao Zheng, Joshua F. Apgar, Bjorn L. Millard, Nancy Zheng, Hong Lu, Jennifer Richardson, Serwer Laura Patterson, Chihunt Wong |
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Rok vydání: | 2018 |
Předmět: | |
Zdroj: | Journal of Clinical Oncology. 36:e14558-e14558 |
ISSN: | 1527-7755 0732-183X |
Popis: | e14558Background: CX-072 is a protease-activatable antibody prodrug directed against programmed cell death ligand 1 (PD-L1). Probody therapeutics (Pb-Txs) are designed to be preferentially activate... |
Databáze: | OpenAIRE |
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