Oxidation of Cinacalcet Hydrochloride by Chloramine-B in Acid Medium: A Kinetic and Mechanistic Study

Autor:	Nichhapurada Kallesha, Kereyagalahally H. Narasimhamurthy, N. Shivakumara, Ningegowda Prasad
Rok vydání:	2021
Předmět:	Cinacalcet Hydrochloride Chemistry General Chemistry Chloramine B Nuclear chemistry
Zdroj:	Asian Journal of Chemistry. 33:2065-2068
ISSN:	0975-427X 0970-7077
DOI:	10.14233/ajchem.2021.23292
Popis:	Kinetic and mechanistic study of cinacalcet hydrochloride by chloramine-B (CAB) in HCl medium at 308 K was the aim of this work. Analyzed the reaction at five different temperatures and determined the thermodynamic parameters using Arrhenius plots. The reaction had a stoichiometry of 1:2 and characterized the oxidation product using chromatographic and spectroscopic methods. The rate law is deduced from the marked effects, which were accompanied by plausible mechanisms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a0818fe62d521d0d90157d2f7a570c1c https://doi.org/10.14233/ajchem.2021.23292 Zobrazit plný text záznamu