Functionalization of 2-bromo-N-benzyl indole via lithium–bromide exchange

Autor:	Inanllely Y. Gonzalez, Jocelyn E. Brown, Ken S. Feldman
Rok vydání:	2015
Předmět:	Indole test chemistry.chemical_compound Nucleophilic addition chemistry Lithium bromide Organic Chemistry Drug Discovery Substrate (chemistry) Surface modification Organic chemistry Biochemistry Combinatorial chemistry
Zdroj:	Tetrahedron Letters. 56:3564-3566
ISSN:	0040-4039
Popis:	The carbofunctionalization of 2-bromo-N-benzyl indole via lithium–bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a06a513a8b913c21ac9e9f917f316964 https://doi.org/10.1016/j.tetlet.2015.01.032 Zobrazit plný text záznamu Full Text from ScienceDirect