ESR spin-trapping studies of free radicals generated by hydrogen peroxide activation of metmyoglobin

Autor:	Albert M. Pearson, Alfred Haug, J. Ian Gray, Yuan Xu, Ali Asghar, Eric A. Grulke
Rok vydání:	1990
Předmět:	Spin trapping Radical substitution Chemistry Radical General Chemistry Photochemistry law.invention chemistry.chemical_compound Myoglobin Metmyoglobin law Moiety General Agricultural and Biological Sciences Electron paramagnetic resonance Hydrogen peroxide
Zdroj:	Journal of Agricultural and Food Chemistry. 38:1494-1497
ISSN:	1520-5118 0021-8561
DOI:	10.1021/jf00097a014
Popis:	The reaction of metmyoglobin (MetMb) with hydrogen peroxide (H 2 O 2 ) generated a free radical that was detectable by ESR at room temperature only in the presence of the spin trap 5,5-dimethyl-1-pyrroline-N-oxyl (DMPO). The formation of the free radical was favored at pH≥7 and was depressed at low pH. The free radical spin-trapped by DMPO may be a ferryl radical or an amino acid free radical originating from the myoglobin moiety
Databáze:	OpenAIRE
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