Use of Colonoscopy to Screen Asymptomatic Adults for Colorectal Cancer
| Autor: | David A. Lieberman, David G. Weiss, John H. Bond, Dennis J. Ahnen, Harinder Garewal, William V. Harford, Dawn Provenzale, Steve Sontag, Tom Schnell, Theodore E. Durbin, Doug B. Nelson, Steve L. Ewing, George Triadafilopoulos, Francisco C. Ramirez, John G. Lee, Judith F. Collins, M. Brian Fennerty, Tiina K. Johnston, Christopher L. Corless, Kenneth R. McQuaid, Richard E. Sampliner, Thomas G. Morales, Ronnie Fass, Robert Smith, Yogesh Maheshwari, Gregorio Chejfec |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Villous adenoma
medicine.medical_specialty medicine.diagnostic_test Adenoma Colorectal cancer business.industry Colonoscopy Rectum General Medicine medicine.disease Gastroenterology Asymptomatic medicine.anatomical_structure Dysplasia Internal medicine medicine medicine.symptom business Veterans Affairs |
| Zdroj: | New England Journal of Medicine. 343:162-168 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejm200007203430301 |
| Popis: | Background and Methods The role of colonoscopy in screening for colorectal cancer is uncertain. At 13 Veterans Affairs medical centers, we performed colonoscopy to determine the prevalence and location of advanced colonic neoplasms and the risk of advanced proximal neoplasia in asymptomatic patients (age range, 50 to 75 years) with or without distal neoplasia. Advanced colonic neoplasia was defined as an adenoma that was 10 mm or more in diameter, a villous adenoma, an adenoma with high-grade dysplasia, or invasive cancer. In patients with more than one neoplastic lesion, classification was based on the most advanced lesion. Results Of 17,732 patients screened for enrollment, 3196 were enrolled; 3121 of the enrolled patients (97.7 percent) underwent complete examination of the colon. The mean age of the patients was 62.9 years, and 96.8 percent were men. Colonoscopic examination showed one or more neoplastic lesions in 37.5 percent of the patients, an adenoma with a diameter of at least 10 mm or a villous... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|