Medicinal applications of Euphorbia umbellata, as an antitumor agent, antiulcerogenic and other applications: Review

Autor:	Laertty Garcia de Sousa Cabral, Rosa Andrea NogueiraLaiso, Thais de Oliveira Conceição, Mercedez Reyes Hernández, Monique Gonçalves Alves, Thalles Anthony Duarte Oliveira, Durvanei Augusto Maria, José Artur Medina
Rok vydání:	2021
Předmět:	Antitumor activity Traditional medicine biology Apoptosis Chemistry biology.protein Euphorbia umbellata Tumor cells Caspase Peroxidase
Zdroj:	Journal of Pharmacognosy and Phytochemistry. 10:29-35
ISSN:	2278-4136 2349-8234
Popis:	The demand for herbal medicines is steadily increasing. Within this perspective, compounds derived from the latex of the species Euphorbia umbellata have acquired a prominence presenting antiulcerogenic, anti-inflammatory, homeostatic activities and mainly antitumor activity. Studies carried out with tumor cells indicate that their fractions and subfractions act by modulating the apoptotic pathway by decreasing the mitochondrial electrical potential, as well as activating caspases 3 and 7. Concomitantly, its antiulcerogenic activity is related to the ability to capture radicals and species reactive oxygen, in addition to its inhibitory action in a peroxidase model. Other studies regarding other functionalities of this species are still in progress.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a0329de4262ce6191640d76bc8d75942 https://doi.org/10.22271/phyto.2021.v10.i2a.13669 Zobrazit plný text záznamu