Activity of gonadotropin-releasing hormone neurons during the preovulatory luteinizing hormone surge
| Autor: | Louise F. McDonnell, Stephen J. Judd, Penelope A. Steele |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class media_common.quotation_subject Pulsatile flow Obstetrics and Gynecology Gonadotropin-releasing hormone Biology Endocrinology Reproductive Medicine Hypothalamus Internal medicine medicine Gonadotropin Luteinizing hormone Ovulation Menstrual cycle media_common Hormone |
| Zdroj: | Fertility and Sterility. 45:179-184 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/s0015-0282(16)49151-x |
| Popis: | We assessed the frequency of luteinizing hormone (LH) pulsatility (reflecting the activity of gonadotropin-releasing hormone [GnRH] neurons in the hypothalamus) in six women during the periovulatory LH surge, in five women during the early follicular phase, and in seven women in the midfollicular phase (MFP) (calculated as being 3 to 8days before the LH surge). Collection of blood at 5-minute, versus 15-minute, intervals allowed detection of a larger number of LH pulses in both the MFP (16, versus 27) and periovulatory phase (POP) (11, versus 22) groups of women, but it made no difference in the early follicular phase (EFP) (10 pulses with both methods). During the EFP, the mean number of LH pulses per 4hours (detected by 5-minute sampling) was 2.0±0.7 (± standard deviation [SD]), and the mean LH amplitude (± SD) was 1.3±0.4IU/l. There was a significant increase in the number of pulses in the MFP group (3.9±1.3 pulses/4hours; P P |
| Databáze: | OpenAIRE |
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