A Propos De Deux Cas D’Insulinome Note Sur L’Effet Hypoclycemiant De La Leucine
Autor: | J Corvilain, N Telerman-Toppet, H Brauman |
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Rok vydání: | 1969 |
Předmět: |
medicine.medical_specialty
geography geography.geographical_feature_category Adenoma business.industry Insulin medicine.medical_treatment General Medicine medicine.disease Islet medicine.anatomical_structure Endocrinology Leucine metabolism Internal medicine Medicine Leucine-induced hypoglycemia Leucine business Pancreas Insulinoma |
Zdroj: | Acta Clinica Belgica. 24:109-122 |
ISSN: | 2295-3337 1784-3286 |
DOI: | 10.1080/17843286.1969.11716708 |
Popis: | SummaryThe findings in two cases of islet tells pancreatic tumors have been presented. In one case, aortography led to accurate localisation of the tumor before operation. In the other case, biological tests are discussed on a physiopathologicai basis. It seems that insulin production by the tumor is usually not stimulated by glucose but well by leucine. This fact could explain the phenomenon of leucine induced hypoglycemia in insulin secreting adenomas. It is also suggested that the insulin secreting capacity of the remaining non tumoral pancreas is depressed during hyperglycemia and diminished tolerance to glucide could he explained by this mechanism. |
Databáze: | OpenAIRE |
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