Évaluation de greffons de bigreffe transplantés en monogreffe
| Autor: | Dimitrios Vordos, M. Such, A. De La Taille, M. Matignon, C. Chahwan, Philippe Grimbert, C. Champy, J. Klapp, A. Hoznek, N Merzeau, L. Salomon |
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| Rok vydání: | 2019 |
| Předmět: |
Kidney
medicine.medical_specialty urogenital system business.industry Urology medicine.medical_treatment 030232 urology & nephrology Renal function medicine.disease Single kidney Surgery Transplantation 03 medical and health sciences surgical procedures operative 0302 clinical medicine medicine.anatomical_structure medicine In patient business Kidney transplantation Dialysis Kidney disease |
| Zdroj: | Progrès en Urologie. 29:340-346 |
| ISSN: | 1166-7087 |
| Popis: | Introduction Kidney transplantation is championed as the gold standard treatment for patients with end-stage kidney disease. According to the biomedical agency, there is an increasing number of patients waiting for kidney transplantation. Faced with organ shortage, the use of marginal grafts may well increase the number of available kidney grafts. Occasionally, during dual kidney graft transplantation, the poor quality of one of the two grafts, or other specific circumstances, may lead to transplantation of only one of the two grafts. We have compared patient outcome concerning single kidney transplantation from an initial dual kidney graft with respect to dual kidney graft transplantation. Material Among 67 patients enrolled for a dual kidney graft, 39 dual kidney grafts (group 1) were compared with 12 grafts performed with only one of the two kidneys of a dual kidney graft (group 2) as well as 15 grafts performed following a classic kidney graft protocol (group 3). Results The survival of grafts was respectively for groups 1, 2 and 3 of 100%, 72,5% and 75,4% (P=0.17). The survival of patients was respectively for groups 1, 2 and 3 of 78.3%, 89.9% and 87.8% (P=0.47). Conclusion Our study suggests that transplantation of a single kidney, initially proposed as dual kidney graft candidate, has satisfying results in terms of graft survival and patient mortality at the expense of poorer renal function in comparison to dual kidney graft. Indeed, there was no significant difference in the survival of patients and grafts. This seems promising taking into consideration that the aim of transplantation in elderly recipients is primarily to avoid dialysis, rather than having optimal post-transplantation kidney function. Level of evidence 4. |
| Databáze: | OpenAIRE |
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