Regenerative processes in the liver of pigs following partial hepatectomy

Autor: V. F. Sidorova
Rok vydání: 1964
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 56:790-793
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00811936
Popis: About 1/8 of the liver 9distal portions of the left lateral and central lobes) were removed in 6 young pigs aged 1.5 months. Regenerating liver was investigated on the 3rd, 14th and 63rd postoperative days. As demonstrated, regeneration of the liver at the early periods was accompanied by the rise of mitotic activity of hepatic cells and hypertrophy of hepatic lobules. Mitoses within the lobule were unevenly distributed—their greatest number was localized in the middle and peripheral zones of the lobule. On the 14th–63rd days of regeneration smaller hepatic lobules were revealed at the wound surface; the possibility of their formation anew was considered. Perhaps, however, the small lobules represented the retained and reconstructed areas of old lobules.
Databáze: OpenAIRE