GLUTAMIC-OXALACETIC TRANSAMINASE OF SERUM IN INFANCY AND CHILDHOOD
Autor: | Robert E. Stanton, Howard A. Joos |
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Rok vydání: | 1959 |
Předmět: | |
Zdroj: | Pediatrics. 24:362-366 |
ISSN: | 1098-4275 0031-4005 |
DOI: | 10.1542/peds.24.3.362 |
Popis: | Activity of glutamic-oxalacetic transaminase in serum (S-GOT) has been evaluated in normal infants and children and in a wide variety of diseases, including convalescent rheumatic fever, renal disease, hemolytic disease, infections and various hepatic disorders. In 46 normal children, the observed range was 7-41 units. The range of normal values in newborn infants was somewhat wider, 29-79 units. Convalescent rheumatic fever and infections not involving the liver were associated with normal S-GOT. S-GOT was normal with the hemolytic diseases in the absence of fulminant hemolysis. It was frequently exceptionally low in association with renal disease, and slightly elevated for a few days after major surgery. S-GOT is elevated in diseases of the liver, but the results are too variable for specific differentiation of hepatic diseases in early life. The test is best employed in conjunction with careful clinical evaluation and with other measures of liver function. |
Databáze: | OpenAIRE |
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