Unicystic adenoid ameloblastoma: A new variant?
| Autor: | Bruna Pizziolo Coura, Carolina Cavaliéri Gomes, Felipe Paiva Fonseca, Wagner Henriques de Castro, Ricardo Santiago Gomez, Roberta Rayra Martins-Chaves |
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| Rok vydání: | 2022 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.diagnostic_test business.industry medicine.disease medicine.disease_cause Adenoid Palpation Benign Odontogenic Neoplasm Pathology and Forensic Medicine Lesion Basal (phylogenetics) medicine.anatomical_structure medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Surgery KRAS Oral Surgery medicine.symptom Ameloblastoma business Infiltration (medical) |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 134:e23-e28 |
| ISSN: | 2212-4403 |
| DOI: | 10.1016/j.oooo.2021.10.005 |
| Popis: | Adenoid ameloblastoma with dentinoid is an uncommon benign odontogenic neoplasm, and its unicystic variant seems to be even rarer. A 34-year-old man was referred for evaluation of an asymptomatic swelling in the posterior maxilla. Intraoral examination showed an expansive lesion, soft to palpation, covered by a normal color mucosa. Cone-beam tomography revealed a well-defined unilocular hypodense tumor involving the left maxillary sinus. Histopathological examination of the surgically excised specimen showed a cystic tumor lined by an ameloblastic-like epithelium containing columnar basal cells with hyperchromatic and polarized nuclei. In some areas of the capsule, the tumor showed mural infiltration by sheets of cells containing central whirling structures. Dentinoid material was also observed in association with ameloblastic-like cells. The tumor was BRAF and KRAS wild-type. Collectively, these findings were consistent with the diagnosis of a unicystic variant of adenoid ameloblastoma with dentinoid. |
| Databáze: | OpenAIRE |
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