γ-Trimethylsilyl-substituted allylzirconcenes in organic synthesis. Stereoselective synthesis of terminal 1,3-butadienes and functionalized vinylsilanes

Autor:	Xian Huang, Jin-Hong Pi
Rok vydání:	2004
Předmět:	Trimethylsilyl Organic Chemistry 1 3-Butadiene One-Step Biochemistry Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Drug Discovery Stereoselectivity Organic synthesis Vinylsilane Conjugate
Zdroj:	Tetrahedron Letters. 45:2215-2218
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.01.053
Popis:	γ-Trimethylsilyl-substituted allylzirconcenes, prepared by hydrozirconation of trimethylsilyl-substituted terminal allenes, react with aldehydes at the γ-position to give 1,3-butadienes in one step with good stereoselectivity and undergo conjugate addition to α,β-unsaturated aromatic ketones at the α-position to selectively afford functionalized vinylsilanes in the presence of catalytic CuBr·SMe 2 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9fd3312a7d5765449f881ca1ae6b09a7 https://doi.org/10.1016/j.tetlet.2004.01.053 Zobrazit plný text záznamu Full Text from ScienceDirect