The new fission converter based epithermal neutron irradiation facility for neutron capture therapy
| Autor: | B. Sutharshan, Thomas H. Newton, S. Sakamoto, K.J. Riley, Otto K. Harling, B. A. Wilson |
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| Rok vydání: | 2001 |
| Předmět: |
inorganic chemicals
Nuclear and High Energy Physics Range (particle radiation) Materials science Fission medicine.medical_treatment Radiochemistry chemistry.chemical_element Atomic and Molecular Physics and Optics Radiation therapy Neutron capture chemistry medicine Neutron Lithium Irradiation Boron |
| Zdroj: | Neutron News. 12:24-26 |
| ISSN: | 1931-7352 1044-8632 |
| DOI: | 10.1080/10448630108244962 |
| Popis: | Neutron capture therapy, usually referred to as boron neutron capture therapy or BNCT, is a promising experimental approach to cancer therapy. BNCT involves the infusion of a non-toxic drug, usually a compound containing B-10, which concentrates preferentially in tumor cells and the subsequent neutron irradiation of the tumor region. Neutrons induce the (n,α)reaction in B-10. This produces two highly energetic ions, lithium and helium, with a combined kinetic energy, which is usually 2.3 MeV. The combined range of these two ions is 12 microns. Typical cells are −10 microns in size and, therefore, the energy of these ions is localized to the origin cell and directly adjacent cells. For this reason, BNCT is considered to be a tumor targeting radiation therapy at the cellular level. |
| Databáze: | OpenAIRE |
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