Noise consideration for cancer marker detection using nanowire

Autor: Nanki Hong, Meyya Meyyappan, Yoon-Ha Jeong, Jeong-Soo Lee, Kihyun Kim, Taiuk Rim, Chang-Ki Baek, Sungho Kim
Rok vydání: 2014
Předmět:
Zdroj: 14th IEEE International Conference on Nanotechnology.
Popis: In this paper, a method to extract the signal-to-noise ratio (SNR) is proposed for the Si nanowire (Si-NW) biologically-active field-effect transistors (BioFETs). We have fabricated the devices using CMOS compatible process and demonstrated specific alpha fetoprotein (AFP) detection using the monoclonal antibody of AFP. The low-frequency noise was measured to calculate the parameter. Using our method, we calculated the noise equivalent voltage and calculated the SNR. The Si-NW BioFET showed a SNR of 15.1dB. These parameters are useful indicators to evaluate FET-type sensor devices.
Databáze: OpenAIRE