Interactions between natural autoantibodies to tumor-associated human ovarian cancer antigen and murine ovarian cancer cells CaO-1

Autor: A. Yu. Toptygin, L. L. Moroz, S. V. Chukanov, F. V. Donenko, S. M. Sitdikova, Yu. S. Lebedin, B. S. Amandzholov, L. V. Manyuk
Rok vydání: 1999
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 127:206-208
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf02433117
Popis: The interactions between tumor cells and autoantibodies to tumor-associated human ovarian cancer antigen isolated from the plasma of a non-cancer patient are demonstrated using an original model of pseudomucinous murine ovarian carcinoma CaO-1. The use of natural auto-antibodies for active immunotherapy of tumors may be more effective and safe than murine monoclonal antibodies to CA 125, because there will be no reaction to a foreign protein.
Databáze: OpenAIRE