Interactions between natural autoantibodies to tumor-associated human ovarian cancer antigen and murine ovarian cancer cells CaO-1
Autor: | A. Yu. Toptygin, L. L. Moroz, S. V. Chukanov, F. V. Donenko, S. M. Sitdikova, Yu. S. Lebedin, B. S. Amandzholov, L. V. Manyuk |
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Rok vydání: | 1999 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 127:206-208 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf02433117 |
Popis: | The interactions between tumor cells and autoantibodies to tumor-associated human ovarian cancer antigen isolated from the plasma of a non-cancer patient are demonstrated using an original model of pseudomucinous murine ovarian carcinoma CaO-1. The use of natural auto-antibodies for active immunotherapy of tumors may be more effective and safe than murine monoclonal antibodies to CA 125, because there will be no reaction to a foreign protein. |
Databáze: | OpenAIRE |
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