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Part I. Pathophysiology Effects of Insulin on the Vascular System Helmut O. Steinberg Effects of Diabetes and Insulin Resistance on Endothelial Functions Zhiheng He, Keiko Naruse, and George L. King Diabetes and Advanced Glycoxidation End-Products Melpomeni Peppa, Jaime Uribarri, and Helen Vlassara The Renin-Angiotensin System in Diabetic Cardiovascular Complications Edward P. Feener PPARs and Their Emerging Role in Vascular Biology, Inflammation, and Atherosclerosis Jorge Plutzky Diabetes and Thrombosis David J. Schneider and Burton E. Sobel Role of Estrogens in Vascular Disease in Diabetes: Lessons Learned From the Polycystic Ovary Syndrome Agathocles Tsatsoulis and Panayiotis Economides Poly(ADP-Ribose) Polymerase Activation and Nitrosative Stress in the Development of Cardiovascular Disease in Diabetes Pal Pacher and Csaba Szabo Adiponectin and the Cardiovascular System Suketu Shah, Alina Gavrila, and Christos S. Mantzoros Nitric Oxide and Its Role in Diabetes Mellitus Michael T. Johnstone and Eli Gelfand Diabetes and Atherosclerosis Maria F. Lopes-Virella and Gabriel Virella The Use of Animal Models to Study Diabetes and Atherosclerosis and Potential Anti-Atherosclerotic Therapies Peter D. Reaven and Wulf Palinski Part II. Clinical A. Risk Factors The Metabolic Syndrome and Vascular Disease S. J. Creely, Aresh J. Anwar, and Sudhesh Kumar Diabetes and Hypertension Samy I. McFarlane, Amal F. Farag, David Gardner, and James R. Sowers Diabetes and Dyslipidemia Asha Thomas-Geevarghese, Catherine Tuck, and Henry N. Ginsberg B. Microcirculation Diabetic Retinopathy Lloyd Paul Aiello and Jerry Cavallerano Diabetic Nephropathy Richard J. Solomon and BijanRoshan Diabetic Neuropathy Rayaz A. Malik and Aristidis Veves Microcirculation of the Diabetic Foot Chantel Hile and Aristidis Veves C. Cardiovascular System: Peripheral Vascular System Epidemiology of Peripheral Vascular Disease Stephanie G. Wheeler, Nicholas L. Smith, and Edward J. Boyko Noninvasive Methods to Assess Vascular Function and Pathophysiology Peter G. Danias and Rola Saouaf Peripheral Vascular Disease in Patients With Diabetes Mellitus Bernadette Aulivola, Allen D. Hamdan, and Frank W. LoGerfo Therapeutic Interventions to Improve Endothelial Function in Diabetes Lalita Khaodhiar and Aristidis Veves D. Cardiovascular System: Cardiac Preoperative Assessment and Perioperative Management of the Surgical Patient With Diabetes Mellitus Alanna Coolong and Mylan C. Cohen Diabetes and Percutaneous Interventional Therapy David P. Lorenz, Joseph P. Carrozza, and Lawrence Garcia Cardiac Surgery and Diabetes Mellitus Tanveer A. Khan, Pierre Voisine, and Frank W. Sellke Heart Failure and Cardiac Dysfunction in Diabetes Lawrence H. Young, Raymond R. Russell, III, and Deborah Chyun Diabetes Mellitus and Heart Disease Michael T. Johnstone and George P. Kinzfogl Index |