The Suppressive Effect of Interferon on the Ability of Mouse Spleen Cells Synthesizing IgE to Sensitize Rat Skin for Heterologous Adoptive Cutaneous Anaphylaxis

Autor:	Johnson Ngan, Spencer H. S. Lee, Leon S. Kind
Rok vydání:	1976
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 117:1063-1066
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.117.4.1063
Popis:	Mouse spleen cells which are synthesizing IgE can sensitize rat skin for HACA.2 When such cells are treated with mouse interferon, their ability to sensitize rat skin is reduced or completely inhibited. Two hundred PRD50 units of interferon reduced HACA reactions by more than 50%; 600 units gave complete inhibition. Interferon may act by inhibiting IgE synthesis and/or release.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9fbc2a7e8b1db1e89dde2751867385ff https://doi.org/10.4049/jimmunol.117.4.1063 Zobrazit plný text záznamu