Progress and Potential Application of Chromophore-Assisted Laser Inactivation

Autor:	TianHua Zhou, MinHua Dou, JiaYu Zhang
Rok vydání:	2014
Předmět:	law Chemistry Chromophore-Assisted Laser Inactivation Protein inactivation Molecule Pharmacology (medical) Laser Photochemistry Photobleaching law.invention
Zdroj:	SCIENTIA SINICA Vitae. 44:364-370
ISSN:	1674-7232
DOI:	10.1360/052014-50
Popis:	Chromophore-assisted laser inactivation (CALI) is a new technique that selectively targets proteins of interest to inactivate their function by engineering proteins and dye molecules that produce reactive oxygen species upon absorption of light. This method is a powerful tool for functional analysis via protein inactivation with high spatial and temporal resolution. Here, we review the underlying photochemical mechanisms and applications of CALI, and discuss its potential value in clinical studies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9f9fdc2ea9dcb84f718e6140009efb51 https://doi.org/10.1360/052014-50 Zobrazit plný text záznamu