The Clinical Efficacy and Safety of Paclitaxel in Adjuvant Therapy of Breast Cancer: A Systematic Review and Meta-Analysis
| Autor: | Ya-Hua Lin, Shao-Hui Cai, Qiu-Tong Tan, Sichao Huang, Jun Xu, Shu-Ting Ao, Yi-Si Li, Hua-Qing Chen |
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| Rok vydání: | 2015 |
| Předmět: |
Oncology
medicine.medical_specialty business.industry Cancer Subgroup analysis medicine.disease law.invention Surgery chemistry.chemical_compound Breast cancer Randomized controlled trial Paclitaxel chemistry law Internal medicine Meta-analysis Inclusion and exclusion criteria medicine Adjuvant therapy business |
| Zdroj: | Journal of Cancer Research Updates. 4 |
| ISSN: | 1929-2279 |
| Popis: | Purpose: To systematically review the clinical efficacy and adverse reactions of Paclitaxel for the treatment of mammary cancer. Math: We searched Web of knowledge, PubMed, VIP information and CNKI (to October 2013) on randomised controlled trial about Paclitaxel for the treatment of mammary cancer and retrieved relevant reference and research material by hand. Two authors independently screened document, extracted data and assessed the quality according to inclusion and exclusion criteria, we finally used the software RevMan 5.2 from Cochrane for Meta-analysis. Result: 18 randomized controlled clinical study were brought into our study according to inclusion and exclusion criteria, including 10712 patients. The result of meta-analysis showed that the odds ratios of Paclitaxel for adjunctive therapy [OR = 1.64, 95% CI (1.40, 1.92), P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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