A randomized phase 2 study of the thrombospondin-mimetic peptide ABT-510 in patients with advanced soft tissue sarcoma (STS)

Autor:	George D. Demetri, D. S. Mendelson, Dawn M. Carlson, Evelyn McKeegan, E. K. Rowinsky, Raymond A. Knight, Laurence H. Baker, M. Lobell
Rok vydání:	2005
Předmět:	chemistry.chemical_classification Cancer Research Thrombospondin Pathology medicine.medical_specialty business.industry Soft tissue sarcoma Phases of clinical research Peptide medicine.disease Oncology chemistry ABT-510 Cancer research Medicine Peptide mimetic In patient business
Zdroj:	Journal of Clinical Oncology. 23:9013-9013
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2005.23.16_suppl.9013
Popis:	9013 Background: ABT-510 is a 9-amino acid peptide that mimics the antiangiogenic activity of the naturally occurring protein, thrombospondin-1. In phase 1, ABT-510 was tolerated at doses up to 260...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9f82c6ccb1cc2d47bbc6ed5882f3138b https://doi.org/10.1200/jco.2005.23.16_suppl.9013 Zobrazit plný text záznamu