| Autor: |
Nathan Wetter, Alexei V. Tkachenko, Robert C Parker, Leyi Wang, Jodi L Silotto, Rashid Bashir, Andrew Pekosz, William C. Sullivan, Ahmed Elbanna, Abigail Conte, Michael Curry, Teresa Kiesel, Awais Vaid, Sandeep Puthanveetil Satheesan, Kenton McHenry, Johnny A. Uelmen, Andreas C. Cangellaris, Nickolas Vance, Matthew A Tomaszewski, Julie A. Pryde, John Lantz, Tong Wang, Moira Nolan, Nigel Goldenfeld, Reubin McGuffin, Zachary J. Weiner, Nahed Ismail, Timothy M. Fan, Carly Skadden, Yukari C. Manabe, Janelle Rear, Andrew Miller, Patricia K Anton, Andrew Greta, Kathleen Munoz, John M Paul, Collin Pitts, Iuliana Bentea, Jessica Black, Lowa Mwilambwe, Sanjay J. Patel, Nil A Parikh, Janise M Phillips, Charlie Simpson, Joseph D. Barnes, Mary Stech, Isaac J Galvan, Joseph T Walsh, Jeremy Busch, Joseph Grohens, Randy L Ballard, Neal J. Cohen, Robert M Healy, Todd J Nelson, Kraig Wagenecht, Fadi G. Alnaji, Robin N Kaler, Mark C Potter, Brittani Gray, Wanda E Ward, MaryEllen Sherwood, Robert J Jones, Rhonda L Lipking, Rebecca L. Smith, Lorenzo M Kindle, Melody Mumford, Mary P Stevens, Melvin R Fenner, Matthew L Robinson, Tina H Skelton, Gary Durack, Stephen B Bryan, Allison C Vance, Agha Mirza, Delaney Foster, Jada Moseley, Erika A. Tyburski, Catherine Best-Popescu, Bruce W. Fouke, Gillian Snyder, Michelle Halla Lore, Paul J. Hergenrother, Jade Mayes, Edith Rosillo, Michael DeLorenzo, Arianna A Holterman, Nicole Gastala, Sergei Maslov, Jessica Breitbarth, Karriem S. Watson, Dustin L Yocum, Leslie N Rye, Madison Conte, Kristin Dohrer, Anna Simon, Ryan Thomas, Hantao Zhang, April Edwards, Therese E. Eggett, John A. Vozenilek, Patrick Kelly, Scott A Genung, James Quisenberry, Jeffrey S. Moore, Karen White, Kayla M Banks, Enrique Valera, Declan Glueck, Richard L. Fredrickson, George N. Wong, Mark Johnson, Timothy L. Killeen, Ian G. Jasenof, Danita B Young, Jamie M Singson, Diana Rose E. Ranoa, Christopher B. Brooke, Susan A. Martinis, Jan E Novakofski, Joseph G Gulick, Janna Pflugmacher, Judes Fleurimont, Julian C Cooper, Hannah Christensen, Ronald S Watkins, Charles Brackett, Nicholas Gallagher, Deborah S Stone, Evette Vlach, David M. Kranz, Jennifer Eardley, Heba H. Mostafa, M. Band, Zhiru Liu, Kelsie J. Green, Martin D. Burke, Chris Harris, Robin L. Holland, Laura Wilhelm-Barr, Aaron Kielbasa, Julie D Steinman, P. Mark Hennessy, Arika D Murray, Scott Vanwingerden, Mayank Garg, Charles H. Smith, Melanie J Loots, Edward Santos, Ashley Hetrick, Brian R Brauer |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.1101/2021.08.03.21261548 |
| Popis: |
In the Fall of 2020, many universities saw extensive transmission of SARS-CoV-2 among their populations, threatening the health of students, faculty and staff, the viability of in-person instruction, and the health of surrounding communities.1, 2 Here we report that a multimodal “SHIELD: Target, Test, and Tell” program mitigated the spread of SARS-CoV-2 at a large public university, prevented community transmission, and allowed continuation of in-person classes amidst the pandemic. The program combines epidemiological modelling and surveillance (Target); fast and frequent testing using a novel and FDA Emergency Use Authorized low-cost and scalable saliva-based RT-qPCR assay for SARS-CoV-2 that bypasses RNA extraction, called covidSHIELD (Test); and digital tools that communicate test results, notify of potential exposures, and promote compliance with public health mandates (Tell). These elements were combined with masks, social distancing, and robust education efforts. In Fall 2020, we performed more than 1,000,000 covidSHIELD tests while keeping classrooms, laboratories, and many other university activities open. Generally, our case positivity rates remained less than 0.5%, we prevented transmission from our students to our faculty and staff, and data indicate that we had no spread in our classrooms or research laboratories. During this fall semester, we had zero COVID-19-related hospitalizations or deaths amongst our university community. We also prevented transmission from our university community to the surrounding Champaign County community. Our experience demonstrates that multimodal transmission mitigation programs can enable university communities to achieve such outcomes until widespread vaccination against COVID-19 is achieved, and provides a roadmap for how future pandemics can be addressed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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