Liver and Biliary Tract Symptomatic, Non-Complicated Gallbladder Stone Disease. Operation or Observation?
| Autor: | Karl Søndenaa, I. Nesvik, J. H. Solhaug, Morten Vetrhus, O. Søreide |
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| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Randomization business.industry General surgery medicine.medical_treatment Gallbladder Gastroenterology Gallbladder Stone law.invention Surgery Clinical trial medicine.anatomical_structure Randomized controlled trial law Medicine Cholecystectomy business Prospective cohort study Watchful waiting |
| Zdroj: | Scandinavian Journal of Gastroenterology. 37:834-839 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.1080/gas.37.7.834.839 |
| Popis: | Background: Cholecystectomy has been recognized as the treatment of choice for symptomatic gallbladder stone disease. Not all patients are cured by an operation and the reason for having the gallbladder removed may rest on common practice rather than evidence-based medicine. The aim was to compare cholecystectomy with observation (watchful waiting) in patients with uncomplicated symptomatic GBS disease. Three-hundred-and-thirty-eight patients were considered for participation in the study; 45 patients were excluded according to predefined criteria and 156 did not join for other reasons. The remaining 137 were randomized to cholecystectomy ( n = 68) or non-operative, expectant treatment ( n = 69). Methods: Randomized patients were contacted regularly and followed for a median of 67 months. All gallstone-related hospital contacts were registered in both randomized and excluded patients. Results: Eight of the patients randomized to cholecystectomy did not undergo operation, while 35 of the patients randomize... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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