A histochemical study of the matrix of long bones of the mouse embryo grown in vitro

Autor:	B. Felluga, A. Mazza, G. Curci
Rok vydání:	1979
Předmět:	chemistry.chemical_classification biology Ossification Endocrinology Diabetes and Metabolism fungi Embryo Matrix (biology) medicine.disease In vitro chemistry Proteoglycan Biochemistry In vivo biology.protein medicine Surgery medicine.symptom Glycoprotein Calcification
Zdroj:	Metabolic Bone Disease and Related Research. 2:65-72
ISSN:	0221-8747
Popis:	A histochemical study of the glycoprotein and proteoglycan components of the matrix of mouse embryo long bones grown in vivo and in vitro has been performed. The comparison between the pattern of ossification in vivo and in vitro indicates that in vitro the synthetic and maturative functions of specific carbohydrate containing substances (CCS) is severely altered. A continuously acting differentiative mechanism is postulated for the in vivo situation. Under in vitro conditions calcification does not occur. This observation, taken together with the presence of altered CCS, indicates that CCS might be involved in the normal calcification mechanism.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9f59003ca77714ba3970007b6a240402 https://doi.org/10.1016/0221-8747(79)90019-5 Zobrazit plný text záznamu