Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry and Tandem Mass Spectrometry. 4. 3-Ring and 4-Ring Isomers
| Autor: | Jody C. May, Tiffany M. Crescentini, Sarah M. Stow, John A. McLean, Jay G. Forsythe, David M. Hercules |
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| Rok vydání: | 2018 |
| Předmět: |
Ion-mobility spectrometry
Electrospray ionization 010401 analytical chemistry 02 engineering and technology 021001 nanoscience & nanotechnology Tandem mass spectrometry Mass spectrometry 01 natural sciences Medicinal chemistry Oligomer 0104 chemical sciences Analytical Chemistry Ion chemistry.chemical_compound chemistry Fragmentation (mass spectrometry) Structural isomer 0210 nano-technology |
| Zdroj: | Analytical Chemistry. 90:14453-14461 |
| ISSN: | 1520-6882 0003-2700 |
| DOI: | 10.1021/acs.analchem.8b04103 |
| Popis: | Matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) is used to characterize methylenedianiline (MDA) 3-ring and 4-ring species. Building on our previous MALDI-MS 2-ring MDA isomer study, here we compare 3-ring and 4-ring electrospray ionization (ESI) and MALDI results. In ESI, 3-ring and 4-ring MDAs each form a single [M + H]+ parent ion. However, in MALDI, each MDA multimer forms three unique precursor ions: [M + H]+, [M•]+, and [M – H]+. In this study, 3-ring and 4-ring MDA precursors are characterized to identify the unique fragment ions formed and their respective fragmentation pathways. In addition to the three possible precursors, the 3-ring and 4-ring species are higher-order oligomer precursors in polyurethane (PUR) production and thus provide additional insight into the polymeric behavior of these PUR hard block precursors. The combination of ion mobility-mass spectrometry (IM – MS) and tandem mass spectrometry (MS/MS) allow the structural characterization of these larger MDA... |
| Databáze: | OpenAIRE |
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