Pharmaceutical microcalorimetry: recent advances in the study of solid state materials

Autor:	John Tetteh, Anthony E. Beezer, Michael A. A. O'Neill, Koji Urakami, JA Connor
Rok vydání:	2004
Předmět:	Isothermal microcalorimetry Materials science business.industry Solid-state Benzoyl peroxide Condensed Matter Physics Calorimeter Chemometrics medicine Physical and Theoretical Chemistry Process engineering business Instrumentation medicine.drug
Zdroj:	Thermochimica Acta. 420:19-22
ISSN:	0040-6031
DOI:	10.1016/j.tca.2003.09.036
Popis:	This paper discusses the theory and experimental application of microcalorimetry to the study of solid state reactions of pharmaceutical importance. The practical example selected is that of formulated products containing benzoyl peroxide – a treatment for acne and athlete’s foot. A newly developed procedure for data analysis is outlined and preliminary results from chemometric-based analysis of complex solid state reaction schemes is presented. Finally, the microcalorimetric requirements for such stability studies are contrasted with the newly emerging multi-channel “chip calorimeters” that operate in the nano range (watts, material, concentration) with high throughput potential.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9f3f6967f57f72809c3ff7cfbad1bf21 https://doi.org/10.1016/j.tca.2003.09.036 Zobrazit plný text záznamu Full Text from ScienceDirect