| Autor: |
Lyudmyla Antypenko, Konstyantyn Shabelnyk, Sergiy Kovalenko |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Current Computer-Aided Drug Design. 19 |
| ISSN: |
1573-4099 |
| DOI: |
10.2174/1573409919666230228122259 |
| Popis: |
Introduction: Agricultural chemicals are impacting health nowadays. Recently, promising synergistic antifungal interaction between tacrolimus and some azole compounds was studied. Method: All descriptors and molecular parameters were obtained by the protocols of swissadme. Result: in the result, the following physicochemical and drug-likeness parameters were calculated. Conclusion: Studied triazoles 1 and 2 showed good ADME characteristics and promising toxicity levels suitable to be checked for in vitro toxicology in case of future advanced results in the agricultural field. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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