Macrophage functions measured by magnetic microparticles in vivo and in vitro

Autor: Wolfgang G. Kreyling, Karl Häussinger, Joachim Heyder, Martin Kohlhäufl, Winfried Möller
Rok vydání: 2001
Předmět:
Zdroj: Journal of Magnetism and Magnetic Materials. 225:218-225
ISSN: 0304-8853
DOI: 10.1016/s0304-8853(00)01261-0
Popis: Monodisperse ferrimagnetic iron-oxide particles of 1.4 μm geometric diameter were used to study alveolar macrophage functions (phagocytosis, phagosome transport) and cytoskeletal integrity in healthy subjects and in patients with idiopathic pulmonary fibrosis as well as in cultured macrophages. Dysfunctions in phagocytosis, in phagosome transport and cytoskeletal integrity correlated with an impaired alveolar clearance and could be induced in vitro by cytoskeletal drugs.
Databáze: OpenAIRE