Molecular mechanisms of the damage effect of pesticides of various structures on target organisms
| Autor: | E. A. Saratovskikh |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
010304 chemical physics Chemistry Stereochemistry Cell Pesticide 010402 general chemistry medicine.disease_cause 01 natural sciences 0104 chemical sciences Metal chemistry.chemical_compound medicine.anatomical_structure Enzyme Biochemistry Mechanism of action Polynucleotide visual_art 0103 physical sciences medicine visual_art.visual_art_medium Physical and Theoretical Chemistry medicine.symptom Genotoxicity Triphosphoric acid |
| Zdroj: | Russian Journal of Physical Chemistry B. 11:652-662 |
| ISSN: | 1990-7923 1990-7931 |
| DOI: | 10.1134/s1990793117040224 |
| Popis: | The results of a study of the mechanism of action of eight pesticides: Zenkor, Lontrel, Roundup, Kusagard, Sethoxydim, Basagran, Tachigaren, and Tilt are presented. It is shown that they form bidentate metal complexes with trace elements. Pesticides and their metal complexes interact with mono-, di-, and polynucleotides and enzyme systems of living organisms. In all cases, two- or three-component complex systems are formed. The formation of a complex with adenosine triphosphoric acid leads to energy deficiency of the cell and suppression of energy metabolism. The pesticides considered are promutagens; that is, they exhibit genotoxicity after metabolic activation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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