| Autor: |
Fu-Min Zhang, Xiang Guo, Yong-Yao Li, Shuang-Hu Wang, Xiao-Ming Zhang, Yong-Qiang Tu, Bao-Sheng Li |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Organic Chemistry Frontiers. 8:2510-2514 |
| ISSN: |
2052-4129 |
| Popis: |
A concise method of synthesizing the tetracyclic core of annotinolide C has been developed. The key steps include a tandem epoxidation/semipinacol rearrangement step to construct a quaternary aza [6.5] spiro ring (rings A and B), an intramolecular aldol reaction to assemble a [3.2.1] bridged ring system, and tandem semireduction/lactonization to form a five-membered lactone D-ring. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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