Character of the reaction of di- and polynucleotides with some pesticides

Autor: E. A. Saratovskikh, B. L. Psikha, R. I. Gvozdev, M. V. Lichina
Rok vydání: 1989
Předmět:
Zdroj: Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 38:1822-1827
ISSN: 1573-9171
0568-5230
DOI: 10.1007/bf00957770
Popis: Lontrel, Sencor, Roundup, Kusagard, Tachigaren, Tilt, and Sethoxydim, as well as the bidentate Cu, Co, Ni, Mo, and Fe complexes of the herbicide Lontrel form molecular complexes with adenine heterocyclic compounds containing di- and polynucleotides. Sencor forms the strongest complexes, and Tilt has the lowest complexing constant. Lontrel, Sencor, Basagran, and Roundup totally destroy the cooperative character of the double helix of native DNA. The overall effect of the pesticides on nucleotides is determined both by the complexing constant with the purine base and by the capacity of the molecule of the pesticide to reach the reaction side located in the depth of the twisted double helix of DNA and RNA.
Databáze: OpenAIRE