PD14-02 IN VIVO SELECTIVITY OF DA-8010 FOR THE BLADDER OVER THE BRAIN: EFFECTS ON BLADDER INTRAVESICAL PRESSURE, BRAIN MUSCARINIC RECEPTOR OCCUPANCY, AND COGNITIVE FUNCTION IN MICE

Autor:	Sangeun Lee, Min Jung Lee, Jun-Hwan Moon, Gi Seon Park, Young Nang Kim, Byung Seok Moon, Yoo Mi Shin, Hyun Soo Park, Hyung Keun Lee, Byung Chul Lee
Rok vydání:	2019
Předmět:	First line therapy Intravesical pressure Overactive bladder Antimuscarinic Agent business.industry In vivo Urology Muscarinic acetylcholine receptor Medicine Cognition Pharmacology business medicine.disease
Zdroj:	Journal of Urology. 201
ISSN:	1527-3792 0022-5347
Popis:	INTRODUCTION AND OBJECTIVES:Antimuscarinic agents are widely used as the first line therapy for overactive bladder (OAB). However, concerns have emerged about side effects of antimuscarinics in cen...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9ef7fb631855022aebedfecdeb948274 https://doi.org/10.1097/01.ju.0000555477.65538.ad Zobrazit plný text záznamu