Geographical differences in survival of dogs with non-Hodgkin lymphoma treated with a CHOP based chemotherapy protocol
Autor: | K. B. Reeds, Heather Wilson-Robles, Jessica Lawrence, Z. M. Wright, C. Saba, Michael O. Childress, S. Gillings, Nikolaos G. Dervisis, Timothy J. Stein, K. R. Vickery, Kristine Burgess, S. Rau, Stephanie E. Schleis, C. J. DeRegis, B. Brugmann, Christine M. Budke, Travis Laver, O. A. Smrkovski, M. Silver, A. Novosad, Janet Lori, G. S. Post, Tasha Miller, Douglas H. Thamm |
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Rok vydání: | 2017 |
Předmět: |
Oncology
medicine.medical_specialty Canine Lymphoma Univariate analysis General Veterinary 040301 veterinary sciences business.industry Incidence (epidemiology) 04 agricultural and veterinary sciences CHOP medicine.disease Non-Hodgkin's lymphoma Lymphoma 0403 veterinary science 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Internal medicine Immunology medicine Progression-free survival business Geographic difference |
Zdroj: | Veterinary and Comparative Oncology. 15:1564-1571 |
ISSN: | 1476-5810 |
Popis: | Background In humans geographical differences in the incidence and presentation of various cancers have been reported. However, much of this information has not been collected in veterinary oncology. Aim The purpose of this study was to determine if a geographic difference in progression free survival exists for dogs with lymphoma treated within the US. Materials and Methods Medical records of 775 cases of canine lymphoma from 3 US regions (west, south and north), treated with CHOP chemotherapy, were retrospectively evaluated. Cases were collected from referral institutions and were required to have received at least one doxorubicin treatment and have follow up information regarding time to progression. Results Significant differences in sex (p = 0.05), weight (p = 0.049), stage (p < 0.001), immunophenotype (p = |
Databáze: | OpenAIRE |
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