Multilocular Thymic Cysts Associated with Thymoma
| Autor: | Yuji Ohtsuki, Katsusuke Ohmori, Jun Iwata, Sheng-Ben Liang, E. Ido, S. Ohtsuka |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Pathology
medicine.medical_specialty Thymoma business.industry Germinal center Cell Biology Thymic cyst medicine.disease Epithelium Pathology and Forensic Medicine Pathogenesis Thymic Tissue medicine.anatomical_structure hemic and lymphatic diseases medicine Microscopic Thymoma Perivascular space business |
| Zdroj: | Pathology - Research and Practice. 192:1283-1287 |
| ISSN: | 0344-0338 |
| DOI: | 10.1016/s0344-0338(96)80170-1 |
| Popis: | The association of multilocular thymic cysts (MTC) with thymoma is exceedingly rare, and the pathogenesis of this combination is controversial. We describe the case of a 42-year-old man with an anterior mediastinal mass found to contain MTC and thymoma. A multilocular cystic mass, measuring 13 x 6.5 x 2 cm, was found in the right lobe of the thymus, and contained a 4.7 x 2 cm thymoma in its center. Microscopic thymomas, lipomatously involuted remaining thymic tissue, and lymphoid follicles with germinal centers were found in the walls of MTC as well as in the left thymic lobe. Non-specific chronic inflammation was also present in the walls. In addition, microcysts, which were only found at the periphery of the thymoma and covered with epithelium, might have been formed secondarily by dilatation of the perivascular spaces and of Hassall's corpuscles. These findings suggest that a chronic inflammatory process was responsible for the early formation and enlargement of this patient's MTC, and that while the cavities of the MTC expanded to various degrees, the thymoma, which originated from one of the microscopic thymomas in the walls of MTC, increased in size, and grew to involve the remaining thymic tissue. |
| Databáze: | OpenAIRE |
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