Prevalence of Extended Spectrum b-Lactamases (ESBL) Producers Among Gram-Negative Bacilli in Wound Infection
| Autor: | Arup Kanti Dewanjee, Towhida Naheen, Zakir Hossain, Khan Mashrequl Alam, Sanjoy Kanti Biswas, Ehsanul Hoque, Arifur Rahman, Abu Hena Md Saiful Karim Chowdhury, Anwar Husain, Abdul Mazed, Nasima Akter, Shakeel Ahmed |
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| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
0301 basic medicine biology medicine.drug_class business.industry 030106 microbiology Antibiotics Esbl production Gram negative bacilli bacterial infections and mycoses biology.organism_classification 01 natural sciences Wound infection Klebsiella spp Microbiology Multiple drug resistance 03 medical and health sciences Minimum inhibitory concentration 010608 biotechnology medicine General Materials Science business Bacteria |
| Zdroj: | Chattagram Maa-O-Shishu Hospital Medical College Journal. 15:26-30 |
| ISSN: | 2306-4919 2305-7890 |
| Popis: | Background: Extended Spectrum b -Lactameses Producing Organisms (ESBLs) are increasing in number and causing more severe infections because of their continuous mutation and multidrug resistance property with limited therapeutic option.Aims and Objectives: Present study was undertaken to detect the prevalence of the ESBLs producing bacteria in wound infection, so as to provide a base line data in treating them & prevent unnecessary use of antibioticsMethods: Isolated gram-negative bacteria initially screened by Minimum Inhibitory Concentration (MIC) ESBLs breakpoints. Then suspected ESBLs producers were confirmed by Phenotypic confirmatory test. Results: 105 (One hundred five) (91.30%) bacterial strains were isolated from 115 samples of wound swab & pus from different patients were studied of which 84(80.00%) were Gram-negative and 21(20.00%) were Gram-positive. Among the isolated Gram-negative bacteria 79(94.05%) were found suspected ESBLs producers of which 54(68.35%) were found as confirmed ESBL producers. The prevalence of ESBLs producing organisms in the present study were found to be 64.29% and Klebsiella spp as most prevalent ESBLs producers.Conclusion: It is essential to report ESBL production along with routine sensitivity reporting, which will help the clinician in prescribing the proper antibiotics.Chatt Shi Hosp Med Coll J; Vol.15 (1); Jan 2016; Page 26-30 |
| Databáze: | OpenAIRE |
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