Highly efficient one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles into spirocyclopropyl pyrazolones

Autor:	Mikhail P. Egorov, Michail N. Elinson, Alexander D. Korshunov, Anatoly N. Vereshchagin
Rok vydání:	2016
Předmět:	010405 organic chemistry Cascade Chemistry Pyrazolones Organic chemistry General Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences
Zdroj:	Mendeleev Communications. 26:19-20
ISSN:	0959-9436
DOI:	10.1016/j.mencom.2016.01.008
Popis:	Bromine-assisted one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles affords medicinally relevant spirocyclopropyl pyrazolones in 60–97% yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9ebb73a60f1ec7e73863ca2ed7336e16 https://doi.org/10.1016/j.mencom.2016.01.008 Zobrazit plný text záznamu Full Text from ScienceDirect