Optimization, characterization and biological properties of phenolic compounds extracted from Rosmarinus officinalis
| Autor: | Muhammad H. Alu’datt, Neveen M. Hussein, Ali Almajwal, Mervat Raweshadeh, Taha Rababah, Sana Gammoh, Mohammad N. Alhamad, Abdul Latief A. Al-Ghzawi, Khalil Ereifej |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
030109 nutrition & dietetics Chromatography Antioxidant biology medicine.medical_treatment Extraction (chemistry) 04 agricultural and veterinary sciences General Chemistry biology.organism_classification 040401 food science Rosmarinus 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology chemistry Officinalis Acetone Caffeic acid medicine Methanol Thymol |
| Zdroj: | Journal of Essential Oil Research. 29:375-384 |
| ISSN: | 2163-8152 1041-2905 |
| Popis: | This study evaluated the optimal conditions for the extraction of phenolics from Rosmarinus officinalis. Phenolic extracts were obtained under extraction conditions in which several parameters were varied (time, temperature, solvents and free and bound forms). The results revealed that the optimum conditions for maximum phenolic content extraction and antioxidant activity were achieved using a mixture of methanol and water at 60 °C/1 h. However, the optimal extraction conditions for phenolics with the highest hypertensive (ACE) or diabetic (α-amylase and α-glucosidase) enzyme inhibitory activity were observed using a mixture of acetone and water for extraction at 40 °C/6 h or methanol at 50 °C/8 h, respectively. The results indicated that the free and bound phenolic compounds had antioxidant, antihypertensive and antidiabetic properties. The predominant free phenolic compound identified in rosemary was thymol, while chlorogenic and caffeic acids were the predominant bound phenolic compounds. |
| Databáze: | OpenAIRE |
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