| Autor: |
Muzaffer Polat, Halil Ural Aksoy, Celil Yilmaz, Aslı Kübra Atasever, Sercan Öztürk, Senem Ayça |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of Dr. Behcet Uz Children s Hospital. |
| ISSN: |
2146-2372 |
| DOI: |
10.5222/buchd.2021.34713 |
| Popis: |
Objective: Treatment of childhood refractory epilepsy is a challenge for clinicians. Lacosamide is a new generation antiepileptic drug which is being used for focal onset seizures of adults and children. Efficacy and safety of the drug for adults have been demonstrated in various studies. The aim of this retrospective cross-sectional study is to evaluate the efficacy and safety of lacosamide in childhood refractory focal seizures in our clinic. Methods: We examined the medical records of 14 patients treated with lacosamide in our clinic between January 2016 and January 2020 in terms of demographic, etiological, neuroimaging findings, responses to treatment, adverse effects and drug-drug interactions. We evaluated the patients as responders to treatment whose seizure frequency decreased ≥%50 after 6 months of lacosamide treatment. Results: In 12 patiens (%85.7) seizure frequency decreased ≥%50 (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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