The indirect confirmation of hyperlipoproteinemia phenotypes II, III and IV
| Autor: | Donald R. Wybenga, James W. Winkelman, Frank A. Ibbott |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
medicine.medical_specialty
Very low-density lipoprotein Triglyceride Lipoprotein electrophoresis Cholesterol Biochemistry (medical) Clinical Biochemistry General Medicine Normal state Biochemistry Phenotype chemistry.chemical_compound Endocrinology chemistry Internal medicine Total cholesterol medicine lipids (amino acids peptides and proteins) Serum cholesterol |
| Zdroj: | Clinica Chimica Acta. 40:121-127 |
| ISSN: | 0009-8981 |
| DOI: | 10.1016/0009-8981(72)90258-6 |
| Popis: | Results of serum cholesterol and triglyceride determinations and lipoprotein electrophoresis usually are compatible with respect to one of the hyperlipoproteinemia phenotypes or with the normal state. In a significant number of cases, however, one parameter is inconsistent with the others. The method presented here offers another criterion by which Types II, III and IV can be distinguished. This procedure measures the cholesterol concentration of the Very Low Density Lipoprotein (VLDL) fraction of serum, (d < 1.006) and expresses it as the percentage of the serum total cholesterol. Results obtained from 207 specimens with lipid and electrophoretic laboratory data characteristic of Types II, III and IV demonstrated non-overlapping ranges of VLDL cholesterol: total cholesterol ratios by the proposed method. All samples assigned as Type III were authenticated by demonstration of the abnormal floating β-lipoprotein. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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